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Product Info Summary
| SKU: | M00910 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Primate |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC-P, WB |
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Product info
Product Name
Anti-Hu CD55 Purified Monoclonal Antibody
SKU/Catalog Number
M00910
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD55 Purified Monoclonal Antibody (Catalog# M00910). Tested in Flow Cytometry, IP, IHC-P, WB application(s). This antibody reacts with Human, Primate.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD55 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00910)
Host
Mouse
Contents
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
MEM-118
Isotype
Mouse IgM
Immunogen
HPB-ALL human T cell line. The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00910 is reactive to CD55 in Human, Primate
Applications
M00910 is guaranteed for Flow Cytometry, IP, IHC-P, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
41.4kDa
Background of CD55/DAF
CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 10 μg/ml.
Immunohistochemistry (paraffin sections): 10 μg/ml.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For CD55 (Source: Uniprot.org, NCBI)
Gene Name
CD55
Full Name
Complement decay-accelerating factor
Weight
41.4kDa
Superfamily
receptors of complement activation (RCA) family
Alternative Names
CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CD55; CR; CRdecay accelerating factor for complement (CD55, Cromer blood group system); CROMDAFcomplement decay-accelerating factor; DAF; decay accelerating factor for complement; TC CD55 CHAPLE, CR, CROM, DAF, TC CD55 molecule (Cromer blood group) complement decay-accelerating factor|CD55 antigen|CD55 molecule, decay accelerating factor for complement (Cromer blood group)|Cromer blood group antigen|Rh blood group D antigen
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD55, check out the CD55 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD55: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD55 Purified Monoclonal Antibody (M00910)
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No publications found for M00910
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Customer Reviews
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